Vnitr Lek 2025, 71(2):124-129 | DOI: 10.36290/vnl.2025.021
Blood pressure variability in hypertension and options for its pharmacological management
- II. interní klinika LF UK a FN Plzeň
Blood pressure (BP) displays a large variability. It can be studied by ambulatory BP monitoring, standardized home BP self measurement or by evaluation of BP measured during repeated office visits. All types of measurement predict future cardiovascular events; variability measured by ambulatory BP monitoring has the strongest predictive power in subjects below 50 years of age. Variability of office BP can be expressed as percentage of visits with achieved target BP; it is ideal to have at least 75%. Antihypertensive drugs have different impact on BP variability; it is decreased by calcium channel blockers, thiazide and thiazide-like diuretics. Therefore, they should make part of combination therapy with other antihypertensives which have rather opposite effects.
Keywords: blood pressure variability, ambulatory blood pressure monitoring, home blood pressure measurement, time to therapeutic range, antihypertensives and blood pressure variability.
Accepted: March 18, 2025; Published: March 27, 2025 Show citation
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