Vnitr Lek 2024, 70(6):344-351 | DOI: 10.36290/vnl.2024.070

Autoantibodies in the diagnosis of autoimmune rheumatic diseases - practical use

Martin Žurek
III. interní klinika - nefrologická, revmatologická a endokrinologická

Autoimmune rheumatic diseases represent a diverse group of conditions that may manifest with the production of autoantibodies, immune dysfunction, and systemic symptoms. Diagnosis can be challenging due to many nonspecific manifestations. A key test used in practice is the detection of organ-nonspecific autoantibodies. Autoantibodies present in individuals with systemic rheumatic diseases can serve not only as markers for classification, diagnosis, and prognosis but also in assessing disease activity and guiding treatment decisions. Autoantibodies often also play a direct role in the pathogenesis of individual diseases.

Keywords: autoimmune rheumatic diseases, organ-nonspecific autoantibodies, antinuclear antibodies, rheumatoid factor, antibodies against citrullinated peptides, antibodies against neutrophil cytoplasm.

Accepted: September 19, 2024; Published: October 3, 2024  Show citation

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Žurek M. Autoantibodies in the diagnosis of autoimmune rheumatic diseases - practical use. Vnitr Lek. 2024;70(6):344-351. doi: 10.36290/vnl.2024.070.
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