Vnitr Lek 2023, 69(6):E4-E11 | DOI: 10.36290/vnl.2023.079

Endoscopic and surgical therapy for obesity

Jan Král^{1, 4}, Filip Doleček³, Kateřina Waloszková¹, Jana Selucká¹, Evžen Machytka¹, Julius Špičák¹, Marek Bužga²

¹ Oddělení pro metabolickou endoskopii, Institut klinické a experimentální medicíny, Praha

² Oddělení fyziologie a patofyziologie, Lékařská fakulta, Ostravská univerzita, Ostrava

³ Oddělení chirurgie, Lékařská fakulta, Ostravská univerzita, Ostrava

⁴ 2. lékařská fakulta Univerzity Karlovy a Fakultní nemocnice Motol, Praha

Obesity is a serious disease whose incidence continues to rise worldwide. Obesity-associated diseases lead to reduced quality of life and increased mortality (high blood pressure, dyslipidemia, type 2 diabetes mellitus, etc.). The treatment of obesity is a multidisciplinary and complex process that requires consistent patient cooperation. Lifestyle change is the cornerstone of successful obesity treatment. Pharmacological therapy has experienced a renaissance in recent years and its role, both in monotherapy and in combination with other methods, will gradually become more important. Endoscopic therapy is a rapidly evolving subfield of digestive endoscopy that offers a variety of new methods to reduce, for example, gastric volume or small bowel bypass. The methods are both effective and have a low risk of complications. Surgical therapy, on the other hand, is highly effective, but is burdened with a higher incidence of complications. Bariatric surgery is primarily for patients with advanced obesity with comorbidities. The aim of this publication is to give a comprehensive review of the current endoscopic and surgical methods in the treatment of obesity.

Keywords: obesity, endoscopy, bariatric surgery, weight loss.

Accepted: October 5, 2023; Published: October 10, 2023  Show citation