Vnitr Lek 2023, 69(5):E25-E29 | DOI: 10.36290/vnl.2023.068

Steroid responsive encephalopathy associated with autoimmune thyroiditis as a cause of acuteencephalopathy

Milan Maretta1, Alexandra Lacková1, Hedviga Wágnerová2, Eva Feketeová1, Zuzana Gdovinová1
1 Neurologická klinika UPJŠ LF a UN LP v Košiciach
2 I. interná klinika UPJŠ LF a UN LP v Košiciach

Steroid-responsive encephalopathy associated with autoimmune thyroiditis (SREAT), known as Hashimoto's encephalopathy (HE), represents a heterogeneous group of neurological and neuropsychiatric symptoms associated with a presence of antithyroid antibodies in case of other causes of encephalopathy were excluded. Clinical symptoms most commonly includes acute onset of encephalopathy, behaviour changes and cognitive dysfunction, epileptic seizures as well as cerebellar and extrapyramidal symptoms. Corticoids provides rapid and sustained therapeutic benefit in most patients and only a few patients require other immunosuppressive therapy such as plasmapheresis, intravenous immunoglobulins, or others. We present the cases of two patients with acute onset of encephalopathy, status epilepticus based on SREAT, with rapid improvement after steroid treatment.

Keywords: SREAT, status epilepticus, steroid therapy.

Accepted: September 4, 2023; Published: September 12, 2023  Show citation

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Maretta M, Lacková A, Wágnerová H, Feketeová E, Gdovinová Z. Steroid responsive encephalopathy associated with autoimmune thyroiditis as a cause of acuteencephalopathy. Vnitr Lek. 2023;69(5):E25-29. doi: 10.36290/vnl.2023.068.
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