Vnitr Lek 2023, 69(2):E23-E25 | DOI: 10.36290/vnl.2023.025
Role of eplerenone in the threatment of cardiovascular diseases
- Kardiovaskulární centrum, Nemocnice Na Homolce, Praha
Eplerenone is a selective mineralocorticoid receptor antagonist. Its approved for the therapy of patients with chronic heart failure with left ventricular systolic dysfunction and for the patients after myocardial infarction complicated by heart failure and left ventricular dysfunction. It´s also recommended for the therapy of primary hyperaldosteronism and the treatment of drug resistant hypertension.
Keywords: eplerenone, mineralocorticoid receptors, heart failure, hyperaldosteronism, resistant hypertension.
Accepted: March 29, 2023; Published: March 30, 2023 Show citation
References
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- SPC Eplerenon. Available from: file:///C:/Users/11366/Downloads/eplerenon‑sandoz‑spc%20(1).pdf.Riziko úmrtí-15 %, p = 0,008Riziko úmrtí a hospitalizace z KV příčin-13 %, p = 0,002Riziko náhlé srdeční smrti-21 %, p = 0,03