Vnitr Lek 2022, 68(1):64-67 | DOI: 10.36290/vnl.2022.009

Advances of the contemporary treatment of hypertension and hypercholesterolemia by a new fixed combination

Hana Rosolová
Centrum preventivní kardiologie UK LF v Plzni, 2. interní klinika FN Plzeň

Parallel occurrence of high blood pressure and high plasma cholesterol level is very frequent, in our population in 30 %, and brings multiplicative higher risk for atherosclerotic cardiovascular diseases. On the other hand the contemporary treatment of them reduces that risk synergically. New fixed combination pill of rosuvastatin and ramipril (Kastel) is very felicitous choice for patients with hypercholesterolemia and mild hypertension, in which two antihypertensive drugs are not required immediatelly.

Keywords: hypertension and hypercholesterolemia treatment, cardiovascular diasease prevention, the fixed combination of ramipril and rosuvastatin.

Published: February 14, 2022  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Rosolová H. Advances of the contemporary treatment of hypertension and hypercholesterolemia by a new fixed combination. Vnitr Lek. 2022;68(1):64-67. doi: 10.36290/vnl.2022.009.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Strehlow K, Wassmann S, Bohm M et al. Angiotensin AT1 receptor over‑expression in hypercholesterolemia. Ann Med 2000;32:386-389. Go to original source... Go to PubMed...
    2. Stulak JM, Lerman A, Caccitolo JA et al. Impaired renal vascular endothelial function in vitro in experimental hypercholesterolemia. Atherosclerosis 2001;154:195-201. Go to original source... Go to PubMed...
    3. Wohlfahrt P, Krajčoviechová A, Bruthans J et al. Hypertenze a hypercholesterolemie v české populaci. Vnitř. Lék. 2016:62:863-867.
    4. Thomas F, Bean K, Guize I et al. Combined effect of systolic blood pressure and serum cholesterol on cardiovascular mortality in young (< 55 years) men and women. Eur Heart J 2002;23:528-535. Go to original source... Go to PubMed...
    5. Neaton JD, Wentworth D. Serum cholesterol, blood pressure, cigarette smoking and death from coronary artery disease overal findings and differences by age for 316 099 white men. MRFIT Research group. Arch Intern Med 1992;152:56-64. Go to original source...
    6. Williams B, Mancia G, Spiering W et al. 2018 ESC/ESH Guidelines for the management of arterial hypertension: The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). Europ Heart J, 2018;39:3021-3104. Go to original source... Go to PubMed...
    7. Borghi C, Cicero f, Bacchelli S et al. Survival of Myocardial Infarction Long‑term Evauation (SMILE) study. Serum cholesterol levels on admission and survival in patients with acute myocardial infarction treated with zofenopril a post hoc analysis of te SMILE tril. Fundam Clin Pharmacol 2009;23:641-648. Go to original source... Go to PubMed...
    8. Mach F, Baigent C, Catapano AL et al. 2019 ESC/EAS Guidelines for the management of dyslipidaemias: lipid modification to reduce cardiovascular risk The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS).Eur Heart J 2019; doi:10.1093/eurheartj/ehz455 Go to original source... Go to PubMed...
    9. Briasoulis A, Agarwal B, Valachis A et al. Antihypertenive effects of statins: a metaanalysis of prospective controlled studies. J Clin Hypertens 2013;15:310-320. Go to original source... Go to PubMed...
    10. Emberson J, Whincup P, Morris R et al. Evaluating the impact of population and high risk strategies for the primary prevention of cardiovascular disease. Eur Heart J 2004;25:484-491. Go to original source... Go to PubMed...

    Return to the content


    Vnitřní lékařství

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.