Vnitr Lek 2020, 66(1):44-48 | DOI: 10.36290/vnl.2020.008
Acute myocardial infarction in a male patient with metabolic syndrome and obstructive sleep apnea syndrome
- II. interní klinika UK, LF v Plzni a Fakultní nemocnice Plzeň
A casuistic of a male, obese smoker, to whom the syndrom of obstructive sleep apnea (OSA) was diagnosed at his age of 32 years, was suffering from acute myocardial infarction at his 50 years. The patient had fulfilled all criteria of metabolic syndrome during time of acute heart attack: visceral obesity, arterial hypertension, mixed dyslipidemia, and type 2 diabetes mellitus. He was never examined by routine screening and then not treated. This patient ranked to the very high total cardiovascular risk subjects before the acute event occured. The growing evidence suggests that OSA may contribute to the metabolic derangements that characterized the metabolic syndrome and high cardiovascular risk. It follows that after syndrome OSA determination, standard risk factors for metabolic syndrome and atherosclerotic cardiovascular disease should be asessed and start preventive lifestyle recommendations and treatment.
Keywords: myocardial infarction, metabolic syndrome, obstructive sleep apnea syndrome.
Published: February 21, 2020 Show citation
References
- Alberti KG, Eckel RH, Grundy SM et al. Harmonizing the Metabolic Syndrome: a Joint Interim Statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009; 120: 1640-1645.
Go to original source...
Go to PubMed...
- Rosolová H. Metabolický syndrom a jeho význam v primární prevenci nemocí s častým výskytem v populaci. CorVasa 2011; 53: 249-252.
Go to original source...
- Gottlieb DJ, Yenokyan G, Newman AB et al. Prospective study of obstructive sleep apnea and incident coronary heart disease and heart failure: the Sleep Heart Health Study. Circulation. 2010; 122: 352-360.
Go to original source...
Go to PubMed...
- Mach E, Baigent C, Catapano AL et al. TaskForceMembers: 2019 ESC/EAS Guidelinesforthe management of dyslipidaemias: lipid modification to reduce cardiovascular risk. The Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS). European Heart Journal (2019): 1-78.
- Tietjens JR, Claman D, Kezirian EJ et al. Obstructive Sleep Apnea in Cardiovascular Disease: A Review of the Literature and Proposed Multidisciplinary Clinical Management Strategy. J Am Heart Assoc. 2019; 8(1): e010440.
Go to original source...
Go to PubMed...
- Heinzer R, Vat S, Marques‑Vidal P et al. Prevalence of sleep‑disordered breathing in the general population: the HypnoLaus study. Lancet Respir Med. 2015;3(4):310-318
Go to original source...
Go to PubMed...
- Mansukhani MP, Covassin N, Somers VK. Apneic Sleep, Insufficient Sleep, and Hypertension. Hypertension. 2019; 73: 744-756
Go to original source...
Go to PubMed...
- Martínez‑García M, Capote F, Campos‑Rodríguez F et al. Effect of CPAP on Blood Pressure in Patients With Obstructive Sleep Apnea and Resistant Hypertension: The HIPARCO Randomized Clinical Trial. JAMA. 2013; 310(22): 2407-2415.
Go to original source...
Go to PubMed...
- Gami AS, Hodge DO, Herges RM et al.Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation J. Am Coll Cardiol 2007; 49: 565-571.
Go to original source...
Go to PubMed...
- Kanagala R, Murali NS, Friedman PA et al. Obstructive sleep apnea and the recurrence of atrial fibrillation. Circulation. 2003; 107: 2589-2594.
Go to original source...
Go to PubMed...
- Zhang L, Hou Y, Po SS. Obstructive Sleep Apnoea and Atrial Fibrillation. Arrhythm Electrophysiol Rev. 2015; 4(1): 14-18.
Go to original source...
Go to PubMed...
- Simantirakis EN, Schiza SI, Marketou ME et al. Severe bradyarrhythmias in patients with sleep apnoea: the effect of continuous positive airway pressure treatment: a long‑term evaluation using an insertable loop recorder. Eur Heart J. 2004; 25: 1070-1076.
Go to original source...
Go to PubMed...
- Gami AS, Olson EJ, Shen WK et al. Obstructive sleep apnea and the risk of sudden cardiac death: a longitudinal study of 10,701 adults. J Am Coll Cardiol. 2013; 62(7): 610-616.
Go to original source...
Go to PubMed...
- Peppard PE, Young T, Palta M et al. Longitudinal study of moderate weight change and sleep‑disordered breathing. JAMA. 2000; 284(23): 3015-3021.
- Foster GD, Sanders MH, Millman R et al. Obstructive sleep apnea among obese patients with type 2 diabetes. Diabetes Care. 2009; 32(6): 1017-1019.
Go to original source...
Go to PubMed...
- International Diabetes Federation. The IDF Consensus Statement on Sleep Apnoea and Type 2 Diabetes. Dostupné z WWW:https://www.idf.org/e‑library/consensus‑statements/62-idf‑consensus‑statement‑on‑sleep‑apnoea‑and‑type-2-diabetes.html
- McEvoy RD, Antic NA, Heeley E et al. CPAP for Prevention of Cardiovascular Events in Obstructive Sleep Apnea. N Engl J Med 2016; 375: 919-931.
Go to original source...
Go to PubMed...