Vnitr Lek 2018, 64(6):588-594 | DOI: 10.36290/vnl.2018.081

Current trends in the diagnosis and treatment of gastroesophageal reflux disease

Radek Kroupa*, Štefan Konečný, Jiří Dolina
Interní gastroenterologická klinika LF MU a FN Brno, pracoviště Bohunice

Gastroesophageal reflux disease and its typical symptoms heartburn and regurgitation is one of the most common gastrointestinal disorders. Besides esophageal symptoms awareness of extraesophageal symptoms is increasing. The diagnosis is usually based on history of symptoms and on endoscopically visible esophageal injury in some patients. Normal endoscopic finding and refractory symptoms on standard treatment should evoke further examination. Proton pump inhibitors have been the mainstay of medical therapy. Long term maintenance treatment may raise awareness of side effects and therapeutic alternatives. This review is focused of current available diagnostic and therapeutic strategies for gastroesophageal reflux disease.

Keywords: Barrett's esophagus; esophageal impedance; esophageal stricture; fundoplication; gastroesophageal reflux; gastroesophageal reflux disease; proton pump inhibitors

Received: October 27, 2017; Accepted: April 18, 2018; Published: June 1, 2018  Show citation

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Kroupa R, Konečný Š, Dolina J. Current trends in the diagnosis and treatment of gastroesophageal reflux disease. Vnitr Lek. 2018;64(6):588-594. doi: 10.36290/vnl.2018.081.
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