Vnitr Lek 2018, 64(1):83-85 | DOI: 10.36290/vnl.2018.013

The current position of hydrochlorothiazide among thiazide and thiazide-like diuretics

Jiří Slíva
Ústav farmakologie 3. LF UK, Praha

Thiazide and thiazide-like diuretics are an important group of drugs used in the treatment of essential arterial hyper-tension. While their beneficial therapeutic effect in monotherapy is evident, they are increasingly used in fixed combinations, particularly with ACE inhibitors or sartans. The aim of this article was to summarize the current status of hydrochlorothiazide and compare its effects with other substances in this subgroup of diuretics.

Keywords: diuretics; HCTZ; hydrochlorothiazide; hypertension; chlorthalidone; indapamide; thiazide

Received: December 30, 2017; Accepted: January 5, 2018; Published: January 1, 2018  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Slíva J. The current position of hydrochlorothiazide among thiazide and thiazide-like diuretics. Vnitr Lek. 2018;64(1):83-85. doi: 10.36290/vnl.2018.013.
Download citation

References

  1. Elliott WJ, Weber RR, Murphy MB. A double-blind, randomized, placebo-controlled comparison of the metabolic effects of low-dose hydrochlorothiazide and indapamide. J Clin Pharmacol 1991; 31(8): 751-757. Go to original source... Go to PubMed...
  2. Elisaf MS, Theodorou J, Pappas H et al. Effectiveness and metabolic effects of perindopril and diuretics combination in primary hypertension. J Hum Hypertens 1999; 13(11): 787-791. Go to original source... Go to PubMed...
  3. Spence JD, Huff M, Barnett PA. Effects of indapamide versus hydrochlorothiazide on plasma lipids and lipoproteins in hypertensive patients: a direct comparison. Can J Clin Pharmacol 2000; 7(1): 32-37.
  4. Krum H, Skiba M, Gilbert RE. Comparative metabolic effects of hydrochlorothiazide and indapamide in hypertensive diabetic patients receiving ACE inhibitor therapy. Diabet Med 2003; 20(9): 708-712. Go to original source... Go to PubMed...
  5. Roush GC, Ernst ME, Kostis JB et al. Head-to-head comparisons of hydrochlorothiazide with indapamide and chlorthalidone: antihypertensive and metabolic effects. Hypertension 2015; 65(5): 1041-1046. Dostupné z DOI: <http://dx.doi.org/10.1161/HYPERTENSIONAHA.114.05021>. Go to original source... Go to PubMed...
  6. Roush GC, Holford TR, Guddati AK. Chlorthalidone compared with hydrochlorothiazide in reducing cardiovascular events: systematic review and network meta-analyses. Hypertension 2012; 59(6): 1110-1117. Dostupné z DOI: <http://dx.doi.org/10.1161/HYPERTENSIONAHA.112.191106>. Go to original source... Go to PubMed...
  7. Kaplan NM. Chlorthalidone versus hydrochlorothiazide: a tale of tortoises and a hare. Hypertension 2011; 58(6): 994-995. Dostupné z DOI: <http://dx.doi.org/10.1161/HYPERTENSIONAHA.111.183525>. Go to original source... Go to PubMed...
  8. Dhalla IA, Gomes T, Yao Z et al. Chlorthalidone versus hydrochlorothiazide for the treatment of hypertension in older adults: a population-based cohort study. Ann Intern Med 2013; 158(6): 447-455. Dostupné z DOI: <http://dx.doi.org/10.7326/0003-4819-158-6-201303190-00004>. Go to original source... Go to PubMed...
  9. Kreeft JH, Langlois S, Ogilvie RI. Comparative trial of indapamide and hydrochlorothiazide in essential hypertension, with forearm plethysmography. J Cardiovasc Pharmacol 1984; 6(4): 622-626. Go to original source... Go to PubMed...
  10. Plante GE, Dessurault DL. Hypertension in elderly patients. A comparative study between indapamide and hydrochlorothiazide. Am J Med 1988; 84(1B): 98-103. Go to original source... Go to PubMed...
  11. Madkour H, Gadallah M, Riveline B et al. Comparison between the effects of indapamide and hydrochlorothiazide on creatinine clearance in patients with impaired renal function and hypertension. Am J Nephrol 1995; 15(3): 251-255. Go to original source... Go to PubMed...
  12. Emeriau JP, Knauf H, Pujadas JO et al. A comparison of indapamide SR 1.5 mg with both amlodipine 5 mg and hydrochlorothiazide 25 mg in elderly hypertensive patients: a randomized double-blind controlled study. J Hypertens 2001; 19(2): 343-350. Go to original source... Go to PubMed...
  13. Semenkin AA, Zhivilova LA, Golevtsova ZS et al. Comparative assessment of hypotensive, metabolic, and endothelial effects of indapamide-retard and hydrochlorothiazide in patients with essential hypertension. Kardiologiia 2006; 46(5): 35-39.
  14. Contard F, Glukhova M, Sabri A et al. Comparative effects of indapamide and hydrochlorothiazide on cardiac hypertrophy and vascular smooth-muscle phenotype in the stroke-prone, spontaneously hypertensive rat. J Cardiovasc Pharmacol 1993; 22(Suppl 6): S29-S34. Go to original source...
  15. Rendu F, Bachelot C, Molle D et al. Indapamide inhibits human platelet aggregation in vitro: comparison with hydrochlorothiazide. J Cardiovasc Pharmacol 1993; 22(Suppl 6): S57-S63. Go to original source...
  16. Vergely C, Walker MK, Zeller M et al. Antioxidant properties of indapamide, 5-OH indapamide and hydrochlorothiazide evaluated by oxygen-radical absorbing capacity and electron paramagnetic resonance. Mol Cell Biochem 1998; 178(1-2): 151-155. Go to original source... Go to PubMed...
  17. Poulsen L, Friberg M, Noer I et al. Comparison of indapamide and hydrochlorothiazide plus amiloride as a third drug in the treatment of arterial hypertension. Cardiovasc Drugs Ther 1989; 3(2): 141-144. Go to original source... Go to PubMed...
  18. Luccioni R, Sever PS, Di PT et al. An equivalence study of the safety and efficacy of a fixed-dose combination of perindopril with indapamide versus fixed-dose combinations of captopril with hydrochlorothiazide and enalapril with hydrochlorothiazide in the treatment of hypertension. J Hypertens 1995; 13(12 Pt 2): 1847-1851. Go to original source...
  19. Cremonesi G, Cavalieri L, Cikes I et al. Fixed combinations of delapril plus indapamide vs fosinopril plus hydrochlorothiazide in mild to moderate essential hypertension. Adv Ther 2002; 19(3): 129-137. Go to original source... Go to PubMed...
  20. Circelli M, Nicolini G, Egan CG et al. Efficacy and safety of delapril/indapamide compared to different ACE-inhibitor/hydrochlorothiazide combinations: a meta-analysis. Int J Gen Med 2012; 5: 725-734. Dostupné z DOI: <http://dx.doi.org/10.2147/IJGM.S35220>. Go to original source... Go to PubMed...




Vnitřní lékařství

Madam, Sir,
please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

I declare:

  1. that I have met the above instruction
  2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited


No

Yes

If your statement is not true, please be aware
that brings the risk of danger to their health or the health of others.