Vnitr Lek 2013, 59(12):1043-1048

Prospective, multicentric, non-interventional study to assess the existing treatment of type 2 diabetes mellitus patients inadequately controlled with metformin monotherapy - KOMETA CZ

Š. Svačina1,*, V. Veselá2
1 III. interní klinika 1. lékařské fakulty UK a VFN Praha, přednosta prof. MUDr. Štěpán Svačina, DrSc., MBA
2 Novartis s.r.o., Praha, vedoucí pracovník MUDr. Richard Vonka

After several years of diabetes, the first line anti-diabetic therapy of metformin usually starts failing. The KOMETA study was a prospective, multicentric, non-interventional epidemiological study in patients with type 2 diabetes mellitus inadequately controlled with metformin therapy. The study was conducted between 2010 and 2011. The study demonstrated a significant improvement in diabetes control, reduction of waist circumference, reduction in blood pressure and adjustment of dyslipidemia compared to baseline. Based on this study, our doctors select anti-diabetic drugs responsibly and they often use medicines without the hypoglycaemia risk. Nevertheless, more than two thirds of patients achieve the HbA1c control of under 6% according to IFCC. The main conclusion of this study is that under standard conditions it is possible to achieve full metabolic control of type 2 diabetic patients over the period of nine months.

Keywords: diabetes treatment; metformin failure; anti-diabetic drugs; dyslipidemia; hypertension

Received: August 26, 2013; Accepted: October 23, 2013; Published: December 1, 2013  Show citation

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Svačina Š, Veselá V. Prospective, multicentric, non-interventional study to assess the existing treatment of type 2 diabetes mellitus patients inadequately controlled with metformin monotherapy - KOMETA CZ. Vnitr Lek. 2013;59(12):1043-1048.
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