Vnitr Lek 2012, 58(Suppl 2):115-126

Iron metabolism and its regulations

D. Vyoral1,2,*, J. Petrák1,2
1 Ústav hematologie a krevní transfuze Praha, ředitel prof. MUDr. Marek Trněný, CSc.
2 Ústav patologické fyziologie 1. lékařské fakulty UK Praha, přednosta prof. MUDr. Emanuel Nečas, DrSc.

Iron is an indispensable element. As a catalytical center in many Fe metalloproteins it participates in almost all biochemical pathways. This element, however is able to initiate the generation of toxic free radicals. This review article summarizes the available knowledge on the mechanisms, regulations and disorders of iron absorption, transport and storage.

Keywords: iron; iron metabolism

Received: May 15, 2012; Published: April 1, 2012  Show citation

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Vyoral D, Petrák J. Iron metabolism and its regulations. Vnitr Lek. 2012;58(Supplementum 2):115-126.
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