Vnitr Lek 2012, 58(7-8):128-134

Diagnosis of heparin-induced thrombocytopenia in the Czech Republic

J. Gumulec
Ústav klinické hematologie FN Ostrava, přednosta prim. MUDr. Jaromír Gumulec

Heparin-induced thrombocytopenia is a prothrombotic adverse effect induced by platelet-activating antibodies against complexes of platelet factor 4 and heparin. Diagnosis rests on a clinical assesment of disease probability and laboratory testing. In this review, I describe some approaches to the evaluation of patients with suspected heparin-induced thrombocytopenia. In conclusion I draw attention to some of the reserves in the diagnostic approaches to this potentially fatal disorder in the Czech Republic.

Keywords: heparin-induced thrombocytopenia; heparin; diagnostic procedure; rapid testing; immunoassay; functional tests

Received: May 21, 2012; Published: July 1, 2012  Show citation

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Gumulec J. Diagnosis of heparin-induced thrombocytopenia in the Czech Republic. Vnitr Lek. 2012;58(7-8):128-134.
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