Vnitr Lek 2012, 58(4):325-328

Acute copper poisoning by suicidal attempt

O. Hloch*, J. Charvát
Interní klinika 2. lékařské fakulty UK a FN Motol Praha, přednosta prof. MUDr. Milan Kvapil CSc., MBA

Voluntary copper poisoning is a rare mode of suicide. We report a case of patient admitted to Metabolic Intensive Care Unit who took fatal dose of copper oxichloride. In his clinical picture dominated gastrointestinal dicomfort with the profused diarrhoea leading to the excessive fluids loss exceeding 10 liters over 24 hours. The renal and liver damages typical for copper intoxication were prevented due to the early intensive treatment (2 hours after ingestion of copper oxichlorid) including the application of copper chelator Succicaptal.

Keywords: copper poisoning; treatment by chelator agent

Received: October 24, 2011; Accepted: December 28, 2011; Published: April 1, 2012  Show citation

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Hloch O, Charvát J. Acute copper poisoning by suicidal attempt. Vnitr Lek. 2012;58(4):325-328.
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    References

    1. Hasan N, Emery D, Baithun SI et al. Chronic copper intoxication due to ingestion of coins: a report of an unusual case. Hum Exp Toxicol 1995; 14: 500-502. Go to original source... Go to PubMed...
    2. Walsh J, Crosson FJ, Bayley M et al. Acute copper intoxication. Pathophysiology and theraphy with a case report. Am J Dis Child 1977; 139: 149-151. Go to original source... Go to PubMed...
    3. Franchitto N, Gandia-Mailly P, Georges B et al. Acute copper sulphate poisoning: A case report and literature review. Resuscitation 2008; 78: 92-96. Go to original source... Go to PubMed...
    4. Faure A, Mathon L, Poupelin JC et al. Acute cupric sulphate intoxication: pathophysiology and therapy about a case report. Ann Fr Anesth Reanim 2003; 22: 557-559. Go to original source... Go to PubMed...
    5. Propst A, Propst T, Feichtinger H et al. Copper-induced acute rhabdomyolysis in Wilson's disease. Gastroenterology 1995; 108: 885-887. Go to original source... Go to PubMed...
    6. Davis GK, Mertz W. Copper. In: Mertz W (Ed). Trace elements in human and animal nutrition. Vol. 1. 5th ed. New York: Academic Press 1987. Go to original source...
    7. U.S. Enviromental Protection Agency. Ambient water quality for copper. Washington, DC: Office of Water regulations and standards. Criteria and Standards Division 1980. Publ. No. PB81-117475.
    8. Eife R, Weiss M, Barros V et al. Chronic poisoning by copper in tap water: I. Copper intoxications with predominantly gastrointestinal symptoms. Eur J Med Res 1999; 28: 219-223.
    9. Spitalny KC, Brondum J, Vogt RL et al. Drinking Water Induced Copper Intoxication in a Vermont Family. Pediatrics 1984; 74: 1103-1106. Go to original source... Go to PubMed...
    10. Araya M, Olivares M, Pizzaro F et al. Community-based randomized double-blind study of gastrointestinal effects and copper exposure in drinking water. Environ Health Perspect 2004; 112: 1068-1073. Go to original source... Go to PubMed...
    11. Jantsch W, Kulig K, Rumack BH. Massive copper sulfate ingestion resulting in hepatotoxicity. J Toxicol Clin Toxicol 1984-1985; 22: 585-588. Go to original source... Go to PubMed...
    12. Müller-Höcker J, Meyer U, Wiebecke B et al. Copper storage disease of the liver and chronic copper intoxication in two futher German infants mimicking Indian childhood cirrhosis. Pathol Res Pract 1988; 183: 39-45. Go to original source... Go to PubMed...
    13. Oldenquist G, Salem M. Parenteral copper sulfate poisoning causing acute renal failure. Nephrol Dial Transplant 1999; 14: 441-443. Go to original source... Go to PubMed...
    14. Stein RS, Jenkins D, Korns ME. Letter: Death after use of cupric sulfate as emetic. JAMA 1976; 235: 801. Go to original source...
    15. Gunay N, Yildirim C, Karcioglu O et al. A series of patients in the emergency department diagnosed with copper poisoning: recognition eqauls treatment. Tahoku J Exp Med 2006; 209: 243-248. Go to original source... Go to PubMed...

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