Vnitr Lek 2011, 57(7-8):655-658

Immunosuppressive therapy and its problems

M. Kuman
Centrum kardiovaskulární a transplantační chirurgie Brno, ředitel doc. MUDr. Petr Němec, CSc.

Immunosuppressive therapy is crucial for successful kidney transplantation. Induction, antirejection and maintenance immunosuppressive therapy are basic types of immunosuppressive therapy. Base of maintenance immunosuppressive therapy are corticoids + tacrolimus + mycofenolate mofetil. Short and long-term adverse effects are present. Drug interaction with macrolids and antimycotics are substantial. Cooperation between transplantologist and other specialists are crucial for adequate immunosuppressive therapy actualization. Lack of correlation and communication may lead to irrecoverable damage to transplanted kidney.

Keywords: immunosuppressive therapy; immunosuppressive agents; adverse effects; interaction; cooperation

Received: June 20, 2011; Published: July 1, 2011  Show citation

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Kuman M. Immunosuppressive therapy and its problems. Vnitr Lek. 2011;57(7-8):655-658.
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    References

    1. Kahan BD, Koch SM. Current immunosuppressant regiment: considerations for critical care. Curr Opin Crit Care 2001; 7: 242-250. Go to original source... Go to PubMed...
    2. Masri MA. The mosaic of immunosuppressive drugs. Mol Immunol 2003; 39: 1073-1077. Go to original source... Go to PubMed...

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