Vnitr Lek 2011, 57(5):456-462
Improvement of quality of life after ablation of longstanding persistent versus paroxysmal atrial fibrillation: results of 2-year follow-up
- 1 II. interní klinika kardiologie a angiologie 1. lékařské fakulty UK a VFN Praha, přednosta prof. MUDr. Aleš Linhart, DrSc.
- 2 Ústav sociálního lékařství a zdravotní politiky Lékařské fakulty UP Olomouc, přednostka doc. PhDr. Kateřina Ivanová, Ph.D.
- 3 Oddělení kardiologie Nemocnice Podlesí, a.s., Třinec, přednosta prim. MUDr. Marian Branny
- 4 I. interní klinika Lékařské fakulty UK a FN Hradec Králové, přednosta prof. MUDr. Jan Vojáček, DrSc.
Aims:
The purpose of the study was to assess quality of life and socio-economic parameters in patients after ablation of paroxysmal versus longstanding persistent atrial fibrillation (AF).
Methods:
The study included 89 patients with paroxysmal AF and 56 patients with longstanding persistent AF who underwent ablation within 1 year, and were afterwards prospectively followed up for 2 years. Quality of life was evaluated by the EQ-5D questionnaire before and every 6 months after ablation.
Results:
Objective, respectively subjective quality of life at baseline was lower in patients with longstanding persistent AF (67 ± 16 vs 71 ± 10; p = 0.01, resp. 64 ± 12 vs 67 ± 16; p = 0.07); however, after 2 years, it exceeded that of the patients with paroxysmal AF (80 ± 17 vs 75 ± 18; p = 0.03; resp. 73 ± 13 vs 70 ± 17; p = 0.18). The baseline-2 year difference in improvement was higher in patients with longstanding persistent AF in both objective (p = 0,001) and subjective component (p = 0.05). Both groups displayed significant decrease in the days of hospitalization, and the days of working incapacity.
Conclusion:
Patients with longstanding persistent AF exhibit worse baseline quality of life than the patients with paroxysmal AF, and higher quality of life improvement after ablation.
Keywords: atrial fibrillation; paroxysmal atrial fibrillation; persistent atrial fibrillation; quality of life
Received: November 16, 2010; Accepted: December 13, 2010; Published: May 1, 2011 Show citation
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