Vnitr Lek 2011, 57(4):402-404

Metabolic surgery - a new approach to the management of selected diseases

M. Fried^1,2,*, K. Doležalová¹

¹ Centrum pro léčbu obezity a metabolických poruch OB kliniky Praha, přednosta prof. MUDr. Martin Fried, CSc.

² 1. lékařská fakulta UK Praha, děkan prof. MUDr. Tomáš Zima, DrSc., MBA

Treatment options for type 2 diabetes have changed dramatically in the past few years. Experimental works followed by evidence based studies proved long-term efficacy of metabolic surgery in type 2 diabetes treatment. Moreover diabetes resolution is not directly correlated with weight loss and occurs independently to it. Large literature metaanalyses showed that type 2 diabetes can be subtantially improved with metabolic surgery in about 85 % of all diabetic patients, out of which can be resolved in more than 75%. Metabolic surgery affects hormonal secretion on multiple levels namely in the small intestine. Restrictive as well as combined and malabsorptive surgical procedures have positive effect on type 2 diabetes improvement as well as on metabolic syndrome, sleep apnea syndrome and on other comorbidities.

Keywords: metabolic surgery; type 2 diabetes mellitus; surgical treatment of diabetes

Received: March 13, 2011; Published: April 1, 2011  Show citation