Vnitr Lek 2011, 57(3):293-298

Microalbuminuria. From diabetes to cardiovascular risk

V. Monhart^1,2

¹ Interní klinika 1. lékařské fakulty UK a ÚVN Praha, přednosta prof. MUDr. Miroslav Zavoral, Ph.D.

² Nefrologická ambulance Synlab Czech s.r.o. Praha

An increased albuminuria level, known as microalbuminuria is associated with a range of diseases, most frequently with diabetes mellitus and hypertension. Microalbuminuria in type 1 diabetes is an early sign of diabetic nephropathy onset, while it tends to be an indicator of the level of cardiovascular risk in type 2 diabetes and essential hypertension. At present, an increased albumin excretion is considered to be a renal symptom of generalized endothelial dysfunction. A simple investigation, not bothersome to a patient, should be performed early and repeatedly in all patients with diabetes and hypertension, as low microalbuminaemia levels can be managed with appropriate treatment.

Keywords: microalbuminuria; diabetes mellitus; hypertension; endothelial dysfunction; cardiovascular risk

Received: January 10, 2011; Published: March 1, 2011  Show citation