Vnitr Lek 2010, 56(Suppl 2):22-26

Langerhans cell histiocytosis in adults

C. Doberauer
Department of Internal Medicine, Evangelische Kliniken Gelsenkirchen, Germany, head Prof. Dr. med. Claus Doberauer

Langerhans cell histiocytosis in adults is a rare disease with potential involvement of all organs with or without organ dysfunction. In our single institution, 95 patients with histologically confirmed LCH were treated. At time of diagnosis, more than 1/3 of the patients had shown multi-system disease. Reactivations of LCH occurred in about 1/4 of the patients within a median of 6 years, especially in other individual organs. For staging and determination of organ dysfunction extensive diagnostic is necessary. There are a lot of treatment options in relation to isolated organ involvement or systemic disease. It makes sense to approach the disease in a multidisciplinary way.

Keywords: Langerhans cell histiocytosis

Received: September 9, 2010; Published: April 1, 2010  Show citation

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Doberauer C. Langerhans cell histiocytosis in adults. Vnitr Lek. 2010;56(Supplementum 2):22-26.
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