Vnitr Lek 2010, 56(Suppl 1):120-122

Changes of the laboratory indicators of hemostasis in hepatopathy

R. Hrabcová1,4,*, P. Kessler2, J. Gumulec1, M. Kouri3
1 Ústav klinické hematologie FN Ostrava, přednosta prim. MUDr. Jaromír Gumulec
2 Oddělení hematologie a transfuziologie Nemocnice Pelhřimov, p.o., přednosta prim. MUDr. Petr Kessler
3 BioMerieux, South Africa, general manager Marcin Kouri
4 SPADIA LAB a.s., Česká republika, ředitel RNDr. Martin Radina

The liver has a central role in hemostasis. It is the major site of synthesis of the coagulation factors, inhibitors and components of fibrinolytic system. The liver also functions as a site for clearance of their activated forms from the circulation. Liver disease leads to a shift in the delicately controlled hemostatic system in both primary and secondary hemostasis.

Keywords: liver disease; thrombocytopenia; platelet dysfunction; coagulation abnormalities; DIC

Received: April 9, 2010; Published: February 1, 2010  Show citation

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Hrabcová R, Kessler P, Gumulec J, Kouri M. Changes of the laboratory indicators of hemostasis in hepatopathy. Vnitr Lek. 2010;56(Supplementum 1):120-122.
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