Vnitr Lek 2010, 56(4):295-300

Acute hyperglycemia and reperfusion therapy in stroke patients

D. Krajíčková
Neurologická klinika Lékařské fakulty UK a FN Hradec Králové, přednosta MUDr. Radomír Taláb, CSc.

Current acute therapies for ischemic stroke are limited. Only a small proportion of stroke patients are eligible to receive reperfusion therapy. Acute hyperglycemia has a deleterious effect in stroke patients by accelerating ischemic brain damage. The complex relationship between hyperglycemia and stroke is discussed. In tPA-treated patients, the acute but not chronic hyperglycemic state may hamper fibrinolytic process, delaying reperfusion of ischemic penumbra. Early measures to reduce hyperglycemia may favor early recanalization.

Keywords: hyperglycemia; reperfusion therapy; acute ischemic stroke

Received: July 1, 2009; Published: April 1, 2010  Show citation

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Krajíčková D. Acute hyperglycemia and reperfusion therapy in stroke patients. Vnitr Lek. 2010;56(4):295-300.
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