Vnitr Lek 2009, 55(Suppl 1):52-58

Paediatric tumours metastasizing to bone marrow and their haematological characterisation

S. Valníček1,*, J. Zapletal1, J. Blatný1, B. Jordanová1, M. Kokeszová1, D. Kodýtková2
1 Oddělení klinické hematologie FN Brno, pracoviště Bohunice, přednosta prof. MUDr. Miroslav Penka, CSc., pracoviště Dětská nemocnice, vedoucí lékař MUDr. Jan Blatný, Ph.D.
2 Klinika dětské onkologie Lékařské fakulty MU a FN Brno, pracoviště Dětská nemocnice, přednosta prof. MUDr. Jaroslav Štěrba, Ph.D.

The paper provides an overview of paediatric tumours most frequently metastasizing to bone marrow, reviews briefly possible clinical and laboratory signs of metastases and lists and evaluates morphological methods of their diagnosis with particular focus on haematological investigations of bone marrow aspirations. The paper briefly touches upon the morphology of the most important tumours in this group and, in attachments, presents their microphotographs with explanatory notes. Possible difficulties faced by the clinicians when evaluating the tumours are highlighted. The authors cite published literature and share experiences from their own practice.

Keywords: paediatric tumours; bone marrow metastases; morphology; bone marrow aspiration

Received: April 10, 2009; Published: February 1, 2009  Show citation

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Valníček S, Zapletal J, Blatný J, Jordanová B, Kokeszová M, Kodýtková D. Paediatric tumours metastasizing to bone marrow and their haematological characterisation. Vnitr Lek. 2009;55(Supplementum 1):52-58.
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