Vnitr Lek 2007, 53(6):694-701

New knowledge in the heredity of autoimmune diabetes. 1st part - Monogenetically determined types of autoimmune diabetes

J. Vavřinec*, J. Vosáhlo
Klinika dětí a dorostu 3. lékařské fakulty UK a FN Královské Vinohrady, Praha, přednosta doc. MUDr. Felix Votava, Ph.D.

The incidence of type 1 diabetes (DM1) varies greatly among different nations and ethnic groups. Precise mapping of DM1 incidence and its trends is useful in the study of the interaction of genetic and non-genetic factors which influence the manifestation and course of the disease. Important progress has been made in the understanding of the mechanisms of autoimmune diabetes by the study of genes and autoimmune forms of monogenetic diabetes.

Keywords: monogenetic autoimmune diabetes mellitus; heredity; APS-I + II; IPEX

Received: December 5, 2006; Accepted: January 17, 2007; Published: June 1, 2007  Show citation

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Vavřinec J, Vosáhlo J. New knowledge in the heredity of autoimmune diabetes. 1st part - Monogenetically determined types of autoimmune diabetes. Vnitr Lek. 2007;53(6):694-701.
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