Vnitr Lek 2007, 53(5):545-547
Metabolic importance of muscles and the role of sports in diabetic patients
- III. interní klinika 1. lékařské fakulty UK a VFN, Praha, přednosta prof. MUDr. ©těpán Svačina, DrSc., MBA
Muscle is a very important tissue in pathogenesis of diabetes and its complications. In future muscle will become a target of novel farmacotherapy of diabetes. Sport in diabetes has important cardiovascular effects and limited metabolic effects. Physical activity in diabetes can induce hypo- and hyperglyceaemia. Dosing scheme for insulin and diet was published for sporting in diabetes. Most important is individual selfmonitoring and adjustment of therapy during sporting activities.
Keywords: insulin therapy during sporting; diet therapy during sporting; effect of sport in diabetes; future of diabetes pharmacotherapy; future drugs influencing muscle in diabetes
Received: December 26, 2006; Published: May 1, 2007 Show citation
References
- Bluher M, Bullen JW jr, Lee JH et al. Circulating adiponectin and expression of adiponectin receptors in human skeletal muscle: associations with metabolic parameters and insulin resistance and regulation by physical training. J Clin Endocrinol Metab 2006; 91: 2310-2316.
Go to original source...
Go to PubMed...
- Haluzík M. Svačina ©. Metabolický syndrom a jaderné receptory PPAR. Praha: Grada 2006.
- Hojlund K, Frystyk J, Levin K et al. Reduced plasma adiponectin concentrations may contribute to impaired insulin activation of glycogen synthase in skeletal muscle of patients with type 2 diabetes. Diabetologia 2006; 49: 1283-1291.
Go to original source...
Go to PubMed...
- Kim JK, Michael MD, Previs SF et al. Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle. Clin Invest 2000; 105: 1791-1797.
Go to original source...
Go to PubMed...
- Maugham RJ, Burke LM. Výľiva ve sportu. Praha: Galén 2002.
- Nagi D. Exercise and sport in diabetes. Chichester: Wiley 2005.
Go to original source...
- Oh YS, Cho KA, Ryu SJ et al. Regulation of insulin response in skeletal muscle cell by caveolin status. J Cell Biochem 2006; 99: 747-758.
Go to original source...
Go to PubMed...
- Svačina ©. Prevence diabetu. Praha: Galén 2003.
- Svačina © et al. Metabolický syndrom. Praha: Triton 2006.