Vnitr Lek 2006, 52(5):451-453

Metabolic PPAR receptors and skin

Š. Svačina
III. interní klinika 1. lékařské fakulty UK a VFN, Praha, přednosta prof. MUDr. Štěpán Svačina, DrSc., MBA

Activators of metabolic PPAR receptors are used in diabetology and lipidology. Many substance influancing PPAR (β/δ) are in research. These substances will be perhaps used in obesitology and in atherosclerosis treatment. Much quicker is approaching the use in dermatology. The effect of receptor stimulation will be used in wound healing and in the treatment of allergic and proliferative diseases. Some realeted substancies influencing heterodimers with RXR or RAR receptors are used in the treatment of acne and skin lymfomas. Dermatology will be after internal medicine the second field where influencing of PPAR receptors will be very important.

Keywords: PPAR β (δ); dermatology; wound healin; acne; skin allergy

Received: August 19, 2005; Accepted: August 19, 2005; Published: May 1, 2006  Show citation

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Svačina Š. Metabolic PPAR receptors and skin. Vnitr Lek. 2006;52(5):451-453.
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