Vnitr Lek 2005, 51(1):72-75

Obesity and metabolic syndrome

D. Zeman

II. interní klinika Lékařské fakulty MU a FN u sv. Anny, Brno, přednosta doc. MUDr. Miroslav Souček, CSc.

Obesity is associated with insulinresistance and metabolic syndrome. The correlation of the presence of abdominal or visceral obesity defined by waist circumference with the occurence of metabolic risk factors and metabolic syndrome is more significant than body mass index. Adipocytokine secretion activity of adipose tissue participates in the pathogenesis of metabolic syndrome. External factors can significantly modify the course of metabolic syndrome disease. Weight reduction is an effective therapeutical intervention. Complex therapeutical approach includes the cognitive behavioral intervention techniques, dietotherapy, regimen exercise measures, pharmacotherapy and surgical bariatric techniques.

Keywords: obesity; visceral obesity; adipose tissue; metabolic syndrome; therapy, treatment of obesity

Received: February 28, 2004; Accepted: July 15, 2004; Published: January 1, 2005  Show citation