Vnitr Lek 2002, 48(3):255-258
[The Brugada syndrome].
- II. interní klinika LF UK Plzen a Fakultní nemocnice, Plzen.
On the case of a patient who had medical care on account of a febrile disease diagnosed as pleuritis the authors draw attention to a relatively new pathological unit described as the "Brugada syndrome". It is a genetically conditioned anomaly of sodium channels, which, when fully expressed, is manifested by a picture resembling right bundle branch block, elevation of ST segment in leads V1-V3 and the occurrence of malignant ventricular arrhythmias or sudden death without structural heart disease. Neither the reported patient nor his family suffered from arrhythmias. The authors present however a typical electrocardiographic picture ad positive test with ajmaline, a substance which by blocking sodium channels can frequently induce latent and variable changes.
Keywords: Bundle-Branch Block, diagnosis, ; Death, Sudden, Cardiac; Electrocardiography; Fever; Humans; Male; Middle Aged; Sodium Channels, genetics, ; Syndrome
Published: March 1, 2002 Show citation