Vnitr Lek 1997, 43(5):317-319

[Heparin cofactor II and thrombophilic conditions].

J Hudecek, E Haµáková, J Ivanková, P Kubisz
Klinika hematológie a transfuziológie MFN a JLF UK.

Heparin co-factor II is in addition to antithrombin III another heparin dependent thrombin inhibitor. This glycoprotein blocks thrombin action not only in haemostasis but also in its other effects. Congenital deficiency of heparin co-factor II was found equally frequently among asymptomatic subjects and patients with thrombotic complications. Although its deficiency probably is not a serious risk factor of thromboembolic disease, it can promote its development in a significant way. The authors describe the case of a child with thrombotic complications and a congenital deficiency of heparin co-factor II.

Keywords: Child, Preschool; Female; Heparin Cofactor II, deficiency, ; Humans; Thrombophilia, blood,

Published: May 1, 1997  Show citation

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Hudecek J, Haµáková E, Ivanková J, Kubisz P. [Heparin cofactor II and thrombophilic conditions]. Vnitr Lek. 1997;43(5):317-319.
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