Vnitr Lek 1997, 43(5):302-306
[Treatment of MALT lymphoma of the digestive tract].
- Klinika hematológie a transfuziológie MFN a JLF UK.
Mucosa-associated lymphoid tissue (MALT) is an autonomous part of the immune system with a specific function, histological structure and circulation of cells. As a result of malignant transformation of this tissue maltomas develop, peripheral extranodal non-Hodgkin lymphomas of B-origin more than two-thirds of which are found in the digestive system. The authors investigated in a retrospective study the effectiveness of different types of treatment of maltomas of the digestive tract with a low and high grade of malignity in 16 patients. It appears that splenectomy is not necessary in these patients and that the effectiveness of primary chemotherapy with a view of inducing complete remission of the disease is comparable with surgical treatment and subsequent adjuvant treatment without deterioration of the patient s life by mutilating surgery. An integral part of treatment of gastric maltomas is eradication of infection caused by Helicobacter pylori.
Keywords: Adult; Aged; Female; Gastrointestinal Neoplasms, therapy, ; Humans; Lymphoma, B-Cell, Marginal Zone, therapy, ; Male; Middle Aged; Retrospective Studies
Published: May 1, 1997 Show citation