Vnitr Lek 1996, 42(4):274-277

[Importance of the expression of the C6 molecule on cells in chronic lymphatic leukemia].

J Krejsek, O Kopecký, V Derner, J Voglová
II. Interní klinika LF UK, Hradec Králové.

The authors made immunophenotyping analyses of blood cells of 50 patients with the diagnosis of B-CLL. Malignant cells contained in all instances HLA DR and CD24 molecules. The superficial molecule CD5 was expressed on cells in 85.7% molecule CD6 on 66.7% cases. By statistical analysis the relationship between selected clinical parameters and expression of surface molecules CD5, CD6 and CD10 was sought. A statistically significantly higher number of leucocytes was found in patients with expression of molecule CD6.

Keywords: Adult; Aged; Antigens, CD /analysis/; Antigens, Differentiation, T-Lymphocyte /analysis/; CD24 Antigen; Female; HLA-DR Antigens /analysis/; Humans; Immunophenotyping; Leukemia, B-Cell /immunology/; Leukemia, Lymphocytic, Chronic, B-Cell /immunology/; Male; Membrane Glycoproteins; Middle Aged

Published: April 1, 1996  Show citation

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Krejsek J, Kopecký O, Derner V, Voglová J. [Importance of the expression of the C6 molecule on cells in chronic lymphatic leukemia]. Vnitr Lek. 1996;42(4):274-277.
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