Vnitr Lek 1996, 42(3):147-149

[Prevention of polymorphous ventricular tachycardia in patients with congenital long QT interval syndrome].

G Kaliská, P Kmec, I Nedělová, M Szentivanyi, J Skamla

Interná klinika A Nemocnice F.D. Roosevelta, Banská Bystrica.

Patients with the Romano-Ward long QT interval syndrome run a high risk of sudden cardiac death. Beta-blockers of the sympathetic nerve are effective treatment. Some patients die suddenly despite this treatment. The treatment of choice is a combination of beta-blockers of the sympathetic nerve and cardiostimulation. The authors describe a group of their own five patients from three families with the Romano-Ward syndrome. The course was favourable. The stimulation rate needed for normalization of the QT interval and a favourable clinical development was 78 +/- 6 imp./min. Based on data in the literature and their own experience the authors recommended combined treatment with beta-blockers and cardiostimulation in patients with the Romano-Ward syndrome, if monotherapy with beta-blockers is not effective.

Keywords: Adrenergic beta-Antagonists, therapeutic use, ; Combined Modality Therapy; Female; Humans; Long QT Syndrome, complications, ; Male; Middle Aged; Pacemaker, Artificial; Tachycardia, Ventricular, etiology,

Published: March 1, 1996  Show citation