Vnitr Lek 1994, 40(8):521-525

[New therapy for osteoporosis].

J Kocián: I. interní klinika IPVZ-FTN, Praha.

The author reviews contemporary drugs and procedures used in the treatment of osteoporosis. Long time known substances such as calcium, vitamin D and fluorides are enlarged by the use of thyrocalcitonin, combined treatment with oestrogens and gestagens in post-climacteric women, biphosphonates, and an essential prerequisite remains burdening of the bones by exercise. As to new preparations, the most promising ones seem to be Ipriflavone and TGF-beta; the use of anabolics is tested again, as well as small doses of parathormone and tamoxifen. In the conclusion the author emphasizes the comprehensive character and prolonged period of treatment of osteoporosis and the necessity of perfect cooperation between patient and physician.