Vnitr Lek 1994, 40(6):350-353

[Tumor markers in the diagnosis of tumors in the subhepatic area].

V Dufek, J Petrtýl, P Klener, J Chmel

I. interní klinika 1. LF UK, Praha.

Concentrations of CA 19-9, CA 50, CA 195 and DUPAN-2 were followed in serum, bile and pancreatic juice of 65 patients with malignant or benign lesions of CBD and/or pancrease. In sera, significant differences between neoplasias and benign lesions were seen only in patients with tumors in stages III. and IV. In the bile, however, the significant increase of DUPAN-2 and CA 195 were present in all stages of cholangiocarcinoma when compared with benign CBD lesions. In the pancreatic juice, the significant increase on of CA 19-9, CA 50 and DUPAN-2 in patients with pancreatic cancer (stages I-IV) could also be evidenced.

Keywords: Adult; Aged; Aged, 80 and over; Antigens, Neoplasm /analysis/; Antigens, Tumor-Associated, Carbohydrate /analysis/; Bile Duct Neoplasms /diagnosis/; Bile Ducts, Intrahepatic; Biomarkers, Tumor /analysis/; Carcinoembryonic Antigen /analysis/; Cholangiocarcinoma /diagnosis/; Female; Humans; Male; Middle Aged; Pancreatic Neoplasms /diagnosis/

Published: June 1, 1994  Show citation