Vnitr Lek 1992, 38(3):276-280

[Wilson's disease and pregnancy].

V Stvrtinová, I Balazovjech, S Hlinstáková, K Hlinsták, A Sasko: II. interná klinika Lekárskej fakulty UK Bratislava.

The authors describe the case of a 27-year-old female patient with Wilson's disease who during penicillinamine treatment became pregnant and was delivered of a healthy infant. The diagnosis of Wilson's disease was confirmed by the finding of a Kayser-Fleischer ring in the cornea and a concurrent serum ceruloplasmin concentration lower than 0.20 g/l. Unrecognized and untreated, the disease is associated with the development of organ complications which in the end prove fatal. On the other hand, early diagnosis and effective treatment throughout life can prevent liver and brain damage and thus enable the patient to live a normal life and women can have a healthy child.