Vnitr Lek 1991, 37(11-12):875-882

[The carbohydrate metabolism and stress hormone response in acute myocardial infarct--its importance in predicting permanent disorders of glucoregulation].

P Lunda, V Zamrazil, A Simecková, P Stolba, P Husek, J Bednár, V Vána

Interní klinika FDL, Praha.

The authors examined in a group of 68 patients with a acute myocardial infarction (without confirmed diabetes) some indicators of the humoral stress reaction and the response of indicators of the carbohydrate metabolism during circulatory stress. After three years they re-examined 48 of these patients with special attention to their carbohydrate metabolism. Based on the assembled results, the authors sought a relationship between findings during the acute circulatory stress and the level of the carbohydrate metabolism after three years. In future diabetics they found during the period of the acute infarction higher levels of immunoreactive insulin, a reduced IRI/blood sugar ratio and a higher excretion of urinary catecholamines. In the OGTT performed one week after the infarction they found a higher sum of C-peptide, a shift of the peak of IRI secretion and reduced IRI/blood sugar ratio. These finding could indicate the development of a permanently impaired glycoregulation and lang-term prognosis of these patients.

Keywords: Adult; Aged; Diabetes Complications; Diabetes Mellitus, diagnosis, ; Female; Glucose Tolerance Test; Hormones, blood, ; Humans; Male; Middle Aged; Myocardial Infarction, complications, ; Prognosis; Stress, Physiological, blood,

Published: November 1, 1991  Show citation