Vnitr Lek 2024, 70(1):55-59 | DOI: 10.36290/vnl.2024.010

Coincidence of liver cirrhosis and Cushing's disease

Lucie Krausová1, Mikuláš Kosák1, Petr Hříbek1, David Netuka2, Václav Masopust2, Tomáš Tůma3, Soňa Fraňková4, Petr Urbánek1
1 Interní klinika 1. LF UK, Ústřední vojenská nemocnice v Praze
2 Neurochirurgická a neuroonkologická klinika 1. LF UK, Ústřední vojenská nemocnice v Praze
3 Radiodiagnostické oddělení, Ústřední vojenská nemocnice v Praze
4 Klinika hepatogastroenterologie, IKEM, Praha

Liver cirrhosis as well as Cushing's syndrome have quite characteristic clinical picture that usually leads to an early diagnosis. Here we present a rather complex case of a 46-year-old patient with an unusual coincidence of Cushing's disease and cirrhosis causing complications during diagnostic evaluation and particularly during the treatment of both diseases.

Keywords: liver cirrhosis, viral hepatitis, Cushing's syndrome, pituitary adenoma.

Accepted: February 9, 2024; Published: February 26, 2024  Show citation

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Krausová L, Kosák M, Hříbek P, Netuka D, Masopust V, Tůma T, et al.. Coincidence of liver cirrhosis and Cushing's disease. Vnitr Lek. 2024;70(1):55-59. doi: 10.36290/vnl.2024.010.
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References

  1. Příbramská V, Husová L. Jaterní cirhóza. Interní Med. 2007;9(11):486-489.
  2. Lata J, Vanásek T, Stibůrek O. Jaterní cirhóza a její lécba [Liver cirrhosis and its treatment]. Vnitr Lek. 2009;55(9):774-778.
  3. Husa P, Šperl J, Urbánek P, et al. Diagnosis and therapy of hepatitis B virus infection: Czech national guidelines. Klin Mikrobiol Infekc Lek. 2017;23(4):148-164. Go to original source...
  4. Buti M, Gonzales A, Riviero-Barcela M, Bourliere M. Management of chronic HBV-HDV patients chronic HBV-HDV infection: A review on new management options. United European Gastroenterol J. 2United European Gastroenterol J. 2023 Dec 2. Epub ahead of print. PMID: 38041549 Go to original source... Go to PubMed...
  5. Wedemeyer H, Manns MP. Epidemiology, pathogenesis and management of hepatitis D: update and challenges ahead. Nat Rev Gastroenterol Hepatol. 2010;7(1):31-40. Go to original source... Go to PubMed...
  6. Savas M, Mehta S, Agrawal N, et al. Approach to the Patient: Diagnosis of Cushing Syndrome. J Clin Endocrinol Metab. 2022;107(11):3162-3174. Go to original source... Go to PubMed...
  7. Brůha R, Šperl J, Urbánek P, et al. Doporučený postup pro léčbu a diagnostiku hepatocelulárního karcinomu. Gastroent Hepatol. 2012;66(2):83-92.
  8. Nieman LK, Biller BM, Findling JW, et al. Endocrine Society. Treatment of Cushing's Syndrome: An Endocrine Society Clinical Practice Guideline. J Clin Endocrinol Metab. 2015;100(8):2807-2831. Go to original source... Go to PubMed...
  9. Casinetti F. Pharmacological Treatment of Cushing's Syndrome. Arch Med Res. 2023 Dec;54(8):102908. doi: 10.1016/j.arcmed.2023.102908. Epub 2023 Nov 15. PMID: 37977919. Go to original source... Go to PubMed...
  10. Becker G, Kocher M, Kortmann RD, et al. Radiation therapy in the multimodal treatment approach of pituitary adenoma. Strahlenther Onkol. 2002 Apr;178(4):173-186. Go to original source... Go to PubMed...
  11. Mehta GU, Ding D, Patibandla MR, et al. Stereotactic Radiosurgery for Cushing Disease: Results of an International, Multicenter Study. J Clin Endocrinol Metab. 2017;102(11):4284-4291. Go to original source... Go to PubMed...
  12. Losa M, Albano L, Bailo M, Barzaghi LR, Mortini P. Role of radiosurgery in the treatment of Cushing's disease. J Neuroendocrinol. 2022 Aug;34(8):e13134. Go to original source... Go to PubMed...
  13. Alwani RA, Schmit Jongbloed LW, de Jong FH, et al. Differentiating between Cushing's disease and pseudo-Cushing's syndrome: comparison of four tests. Eur J Endocrinol. 2014;170(4):477-486. Go to original source... Go to PubMed...




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