Vnitr Lek 2007, 53(5):540-544

Exercise therapy for patients with metabolic syndrome

H. Svačinová
Klinika funkční diagnostiky a rehabilitace Lékařské fakulty MU a FN u sv. Anny, Brno, přednostka prof. MUDr. Jarmila Siegelová, DrSc.

The author presents a list of physical activity effects in metabolic and cardiovascular adaptation and current knowledge of the molecular mechanism of the effect of exercise on insulin resistance. The main principles for the prescription of exercise therapy for patients with metabolic syndrome are presented. The role of patient motivation and compliance is emphasised as part of a complex approach to the treatment of metabolic syndrome; it has a substantial influence on the results of treatment.

Keywords: metabolic syndrome; physical activity; insulin resistance

Received: July 21, 2006; Published: May 1, 2007  Show citation

ACS AIP APA ASA Harvard Chicago Chicago Notes IEEE ISO690 MLA NLM Turabian Vancouver
Svačinová H. Exercise therapy for patients with metabolic syndrome. Vnitr Lek. 2007;53(5):540-544.
Share...
Download citation
  • BibTeX (.bib)
  • Bookends (.ris)
  • EasyBib (.ris)
  • EndNote (.enw)
  • EndNote 8 (.xml)
  • ISI WoS (.isi)
  • Medlars (.medlars)
  • Mendeley (.ris)
  • MODS (.xml)
  • Papers (.ris)
  • RefWorks (.txt)
  • RefManager (.ris)
  • RIS (.ris)
  • MS Word (.xml)
  • Zotero (.ris)
    • Open full article

    References

    1. Reaven GM. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988; 37: 1595-1607. Go to original source... Go to PubMed...
    2. Wannamethee SG, Shaper AG, Walker M. Changes in physical activity, mortality and incidence of coronary heart disease in older men. Lancet 1998; 30: 1603-1608. Go to original source... Go to PubMed...
    3. Haapanen N, Miilunpalo S, Vuori OP et al. Association of leisure time physical activity with the a risk of coronary heart disease, hypertension and diabetes in middle-aged men and women. Int J Epidemiol 1998; 27: 335-336. Go to original source...
    4. Lee IM, Rexrode KM, Cook NR et al. Physical activity and coronary heart disease in women: is "no pain, no gain" passe? JAMA 2001; 285: 1447-1454. Go to original source... Go to PubMed...
    5. Laukkanen JA, Lakka TA, Raurama P et al. Cardiovascular fitness as a predictor of mortality in men. Arch Intern Med 2001; 26: 825-831. Go to original source... Go to PubMed...
    6. Blair SN, Kampert JB, Kohl HW 3rd et al. Influences of Cardiorespiratory Fitness and Other Precursors on Cardiovascular Disease and All-Cause Mortality in Men and Women. JAMA 1996; 276: 205-210. Go to original source...
    7. Laaksonen DE, Lakka HM, Salonen JT et al. Low Levels of Leisure-Time Physical Activity and Cardiorespiratory Fitness predict development of the Metabolic Syndrome. Diabetes Care 2002; 25: 1612-1618. Go to original source... Go to PubMed...
    8. Lakka TA, Laaksonen DE, Lakk HM et al. Sedentary Life Style, Poor Cardiorespiratory Fitness, and the Metabolic Syndrome. Med Sci Sports Exerc 2003; 8: 1279-1286. Go to original source... Go to PubMed...
    9. Whaley MH, Kampert JB, Kohl HV 3rd et al. Physical fitness and clustering of risk factors associated with the metabolic syndrome. Med Sci Sports Exerc 1999; 31: 287-293. Go to original source... Go to PubMed...
    10. Lee DD, Blair SN, Jackson AS. Cardiorespiratory fitness, body composition, and all cause and cardiovascular disease mortality in men. Am J Clin Nutr 1999; 69: 373-380. Go to original source... Go to PubMed...
    11. Ploug T, Stallknecht BM, Pedersen O et al. Effects of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle. Am J Physiol 1990; 259: 778-786. Go to original source... Go to PubMed...
    12. Banks EA jr, Brozinick JT, Yaspelkis BB 3rd et al. Muscle glucose transport, GLUT-4 content, and degree of exercise training in obese Zucker rats. Am J Physiol 1992; 263: E1010-E1015. Go to original source... Go to PubMed...
    13. Henriksen EJ. Invited review: effects of acute exercise and exercise training on insulin resistance. J Appl Physiol 2002; 93: 788-796. Go to original source... Go to PubMed...
    14. Houmard JA, Shinebarger MH, Dolan PL et al. Exercise training increases GLUT-4 protein concentration in previously sedentary middle-aged men. Am J Physiol 1993; 264: E896-E901. Go to original source... Go to PubMed...
    15. Holmes B, Dohm GL. Regulation of GLUT4 Gene Expression during Exercise. Med Sci Sports Exerc 2004; 7: 1202-1206. Go to original source... Go to PubMed...
    16. Krook A, Wallberg-Henriksson H, Zierath JR. Sending the Signal. Molecular Mechanisms Regulating Glucose Uptake. Med Sci Sports Exerc 2004; 7: 1212-1217. Go to original source... Go to PubMed...
    17. Wojtaszevski JFP, Birk JB, Frosig Ch et al. 5'AMP activated protein kinase expression in human skeletal muscle: effects of strength training and type 2 diabetes. J Physiol 2005; 564: 563-573. Go to original source... Go to PubMed...
    18. Dengel DR, Pratley RE, Hagberg JM et al. Distinct effects of aerobic exercise training and weight loss on glucose homeostasis in obese sedentary men. J Appl Physiol 1996; 81: 318-325. Go to original source... Go to PubMed...
    19. Holloszy JO, Schultz J, Kusnierkiewicz J et al. Effects of exercise on glucose tolerance and insulin resistance. Acta Med Scand 1986; Suppl 711: 55-65. Go to original source... Go to PubMed...
    20. Hughes VA, Fiatrone MA, Fielding RA et al. Exercise increases muscle GLUT-4 levels and insulin action in subjects with impaired glucose tolerance. Am J Physiol 1993; 264: E855-E862. Go to original source... Go to PubMed...
    21. Kelley DE, Goodpasture BH Effects of exercise on glucose homeostasis in Type 2 diabetes mellitus. Med Sci Sports Exerc 2001; 33(Suppl 6): S495-S501. Go to original source... Go to PubMed...
    22. Howorka K, Pumprla J, Haber P et al. Effects of physical training on heart rate variability in diabetic patients with various degrees of cardiovascular autonomic neuropathy. Cardiovasc Res 1997; 34: 206-214. Go to original source... Go to PubMed...
    23. Svačinová H, Siegelová J, Olšovský J et al. Baroreflex sensitivity in patients with type 2 diabetes mellitus: effect of exercise. Scripta medica LF MU Brno 2002; 4: 209-213.
    24. Miller WJ, Shermann WM, Ivy JL. Effect of strength training on glucose tolerance and post-glucose insulin response. Med Sci Sports Exerc 1984; 16: 539-543. Go to original source...
    25. Fluckey JD, Hickey MS, Brambrink JK et al. Effects of resistance exercise on glucose tolerance in normal and glucose-intolerance subjects. J Appl Physiol 1994; 77: 1087-1092. Go to original source... Go to PubMed...
    26. Maiorana A, O'Driscoll G, Goodman C et al. Combined aerobic and resistance exercise improves glycemic control and fitness in type 2 diabetes. Diabetes Res Clin Pract 2002; 2: 115-123. Go to original source... Go to PubMed...
    27. Hejnová J, Majerčík M, Richterová B et al. Vliv silově dynamického tréninku na inzulinovou rezistenci u jedinců s obezitou a diabetem II. typu. DMEV 2003 (Suppl 3): 38.
    28. Elbl L, Chaloupka V, Nehyba S et al. Význam kombinovaného rehabilitačního programu u nemocných s chronickou ischemickou chorobou srdeční. Vnitř Lék 2005; 51: 957-964.
    29. Jančík J, Svačinová H, Dobšák P et al. Kombinovaný trénink u nemocných se systolickou dysfunkcí levé komory srdeční. Vnitř Lék 2003; 49: 280-284. Go to PubMed...
    30. Máček M, Máčková J. Může pravidelná pohybová aktivita prodloužit život? Med Sport Boh Slov 1999; 8: 65-71.
    31. Rosolová H. Deprese a metabolický syndrom. In: Svačina Š et al. Metabolický syndrom. Praha: Triton 2006: 166-168.
    32. Svačinová H, Olšovský J, Žáčková V et al. Vliv tréninku chůzí na aerobní kapacitu a krevní lipidy u diabetiků 2. typu. Vnitř Lék 2003; 49: 205-209. Go to PubMed...
    33. Špác J. Je současný tělesný trénink nezbytnou součástí léčby chronické ICHS i v 21. století? - editorial. Vnitř Lék 2005; 51: 930-933.
    34. Říhová M. Pohyb jako prevence i terapie ve středověku (1). Čas Lék Čes 1999; 138: 374-375.

    Return to the content


    Vnitřní lékařství

    Madam, Sir,
    please be aware that the website on which you intend to enter, not the general public because it contains technical information about medicines, including advertisements relating to medicinal products. This information and communication professionals are solely under §2 of the Act n.40/1995 Coll. Is active persons authorized to prescribe or supply (hereinafter expert).
    Take note that if you are not an expert, you run the risk of danger to their health or the health of other persons, if you the obtained information improperly understood or interpreted, and especially advertising which may be part of this site, or whether you used it for self-diagnosis or medical treatment, whether in relation to each other in person or in relation to others.

    I declare:

    1. that I have met the above instruction
    2. I'm an expert within the meaning of the Act n.40/1995 Coll. the regulation of advertising, as amended, and I am aware of the risks that would be a person other than the expert input to these sites exhibited

    No
    Yes

    If your statement is not true, please be aware
    that brings the risk of danger to their health or the health of others.