Vnitr Lek 1999, 45(1):40-45

[Homocysteine--a routine biochemical parameter in cardiovascular diseases?].

D Gábor, J Hrnciar, I Hricová, M Zacharová
Oddelenie klinickej biochémie NsP F. D. Roosevelta, Banská Bystrica.

An elevated level of total homocysteine (tHcy) in blood-hyperhomocysteinemia, is prevalent and strong risk factor for atherosclerotic vascular disease in the coronary, cerebral and peripheral vessels and for thromboembolism (arterial and venous). Elevated total homocysteine confers a graded risk with no threshold, is independent of but may enhance the effect of conventional risk factors. Hyperhomocysteinemia seems to be a particularly strong predictor of cardiovaskular mortality. Supplementation with B-vitamins, in particular with folic acid, is an efficient, safe and inexpensive means to reduce an elevated total homocysteine level.

Keywords: Arteriosclerosis, blood, ; Cardiovascular Diseases, blood, ; Homocysteine, blood, ; Humans; Risk Factors

Published: January 1, 1999  Show citation

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Gábor D, Hrnciar J, Hricová I, Zacharová M. [Homocysteine--a routine biochemical parameter in cardiovascular diseases?]. Vnitr Lek. 1999;45(1):40-45.
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